The Alternatives Research & Development Foundation

Established in 1993, the Alternatives Research & Development Foundation (ARDF) has been a mainstay of support for developing alternatives to animal-based methods in science. Through grant programs, achievement awards and sponsorship of scientific conferences, ARDF advances high quality scientific research that aims to replace and reduce the use of animals.

Focused on exploring non-animal methods and models, ARDF works constructively with partners in the science community to bring alternatives technology and compassion to modern biomedical research, product testing, and classroom laboratories.

ARDF Strategy


The ARDF Annual Open Grant Program was established to fund research projects that develop alternative methods or utilize an alternative approach in research, testing or education. Over $4 million in grants have been awarded to date.

ARDF's new Alternatives in Research (AiR) Challenge program will stimulate innovation in alternative methods, focused on biomedical research.


ARDF works to promote alternatives through the sponsorship of scientific meetings across the globe, participation in regulatory and industry meetings, and providing free consultations with media representatives, scientists, and government officials. ARDF also engages in legal advocacy to accelerate acceptance and utilization of alternative methods, such as its successful legal petitions to National Institutes of Health to require its grantees to produce monoclonal antibodies via in vitro methods, as opposed to traditional mouse ascites.


Recognizing individuals in the scientific community who have made extraordinary contributions to the advancement of alternatives, ARDF rewards scientists through its William and Eleanor Cave Award.


Sue A. Leary | President

Sue A. Leary has been President and CEO of ARDF since 1995. She has a B.S. in Biology and M.S. in Nonprofit Management. Her career has focused on coordination of programs and services; education and advocacy; administration and planning; and membership development in nonprofit organizations. Since 1995, she has served as President of the Alternatives Research & Development Foundation (ARDF) and its affiliate, American Anti-Vivisection Society (AAVS). Ms. Leary is Executive Editor of the AV Magazine, and Chair of the Coalition for Consumer Information on Cosmetics (CCIC), which operates the Leaping Bunny Program. She has served on a number of boards, including the Global Federation of Animal Sanctuaries.

Angela N. Hvitved | Scientific Consultant

Angela N. Hvitved, PhD, MA joined ARDF as a Program Director in 2022. Previously she worked as a scientific review consultant managing review for clinical trial proposals. Before moving into scientific review and administration, she served as a Public Health Advisor at the U.S. Department of Health and Human Services (HHS) Office for Human Research Protections (OHRP). Prior to that, she worked as a Health Science Policy Analyst at the National Institutes of Health (NIH), where she covered a broad range of policy areas. Dr. Hvitved received a PhD in Biochemistry and Cell Biology from Rice University and a MA in Philosophy from Johns Hopkins University.

Board of Directors

Sue A. Leary | President

Joseph Ludwig | Vice President

Aaron McIntyre | Treasurer

Denise Cowie | Secretary

Nadia Adawi, Esq.

Robert Finn

Frank Krafchik

Contact Us

eMail |

Telephone | 215-887-8076

Postal Mail | 801 Old York Road, Suite 218, Jenkintown, PA 19046




Postal Mail

801 Old York Road, Suite 218, Jenkintown, PA 19046